Microwave-assisted slipping synthesis of fluorescent squaraine rotaxane probe for bacterial imaging.
نویسندگان
چکیده
Microwave heating accelerates quantitative squaraine rotaxane formation by slipping and facilitates production of a bacterial imaging probe with zinc dipicolylamine targeting ligands.
منابع مشابه
Efficient synthesis of fluorescent squaraine rotaxane dendrimers.
A squaraine rotaxane scaffold with four alkyne groups is readily converted into a range of dendritic architectures using high-yielding copper-catalyzed alkyne azide cycloaddition (CuAAC) chemistry. A convergent synthesis approach is more efficient than a divergent pathway. Dendritic squaraine rotaxanes with peripheral amine groups can be further functionalized to produce multivalent deep-red fl...
متن کاملSquaraine-derived rotaxanes: highly stable, fluorescent near-IR dyes.
Squaraines are fluorescent, near-IR dyes with promising photophysical properties for biomedical applications. A limitation with these dyes is their inherent reactivity with nucleophiles, which leads to loss of the chromophore. Another drawback is their tendency to form nonfluorescent aggregates in water. Both problems can be greatly attenuated by encapsulating the dye inside an amide-containing...
متن کاملSquaraine rotaxane as a reversible optical chloride sensor.
A mechanically interlocked squaraine rotaxane is comprised of a deep-red fluorescent squaraine dye inside a tetralactam macrocycle. NMR studies show that Cl(-) binding to the rotaxane induces macrocycle translocation away from the central squaraine station, a process that is completely reversed when the Cl(-) is removed from the solution. Steady-state fluorescence and excited-state lifetime mea...
متن کاملSquaraine rotaxanes with boat conformation macrocycles.
Mechanical encapsulation of fluorescent, deep-red bis(anilino)squaraine dyes inside Leigh-type tetralactam macrocycles produces interlocked squaraine rotaxanes. The surrounding macrocycles are flexible and undergo rapid exchange of chair and boat conformations in solution. A series of X-ray crystal structures show how the rotaxane co-conformational exchange process involves simultaneous lateral...
متن کاملThiosquaraine rotaxanes: synthesis, dynamic structure, and oxygen photosensitization.
Thiosquaraine dyes have sulfur atoms instead of oxygens on the central squaraine core, and they are powerful singlet oxygen photosensitizers. Stability studies show that they are susceptible to attack by nucleophiles. This problem was circumvented by preparing a mechanically interlocked thiosquaraine rotaxane. NMR studies of the rotaxane indicate an unusual dynamic molecular structure due to a ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 46 7 شماره
صفحات -
تاریخ انتشار 2010